Best Longevity & Anti-Aging Telehealth: Graded & Ranked
We graded the providers that actually offer NAD+, sermorelin, rapamycin, metformin and GLP-1 protocols on what matters once the marketing fades: a transparent price, a real longevity line rather than a weight-loss menu, genuine clinical review, and real human support. The full report card is below — every graded provider, its marks and its price, before a single review.
Read the grade, not the order. The letter is computed from the marks printed on each row — price transparency, whether the provider actually sells a longevity line, clinical oversight, pharmacy identification and human support, with the first two weighted double — and from nothing else. A provider that sells no NAD+, peptides, hormone therapy or longevity diagnostics cannot reach an A here however clean its billing is. A provider earns the same letter whether or not we are paid by it; the calculation cannot see the difference. Order is a separate thing from the letter, and compensation can influence it — which we disclose rather than leave you to infer (disclosure). So a paid row can and does sit above a better-graded unpaid one — the letter is where you settle it. Required lab work is shown as a trade-off and scores neither way.
Grade A
7 providers · a real longevity line, a published month-to-month price, and oversight or support inside it
Marks restate what each provider publishes on its own site, verified in 2026 and subject to change without notice. “Flat price” means one all-in figure with no separate membership, baseline assessment or lab fee. “Longevity: Core” means NAD+, peptides or sermorelin, hormone optimization or longevity diagnostics are a published line of the business — read off its own catalogue, not its positioning; “Partial” means something adjacent but none of those. Providers we have no commercial tie to are linked with plain referral attribution rather than a paid link. A grade measures provider quality, value and transparency — it is not a claim that any of these therapies extends human lifespan.
A necessary caveat. Most longevity interventions — NAD+, sermorelin and other GH-secretagogues, rapamycin and metformin for healthy adults — are clinically unproven to extend human lifespan. Only GLP-1 receptor agonists have hard cardiovascular-outcome trials behind them. This ranking grades provider quality, value, and transparency — it is not a claim that these therapies make you live longer. Read what the evidence actually shows before you start.
FTC disclosure
Funding, and what it moves
Funding
Affiliate and referral links, routed through the Katalys network. Start a treatment or buy a product through one and we may earn a commission — at no additional cost to you.
Grading
The letter is computed from a provider's own published terms — the marks printed beside it — and the calculation is not given, and cannot read, whether we are paid. Ordering is a separate decision, and compensation can influence it.
What money can't move
No payment buys a kinder write-up or a better letter. Prices are the ones the provider publishes, unflattering findings stay in, and paid providers appear in every grade band we publish — including the lowest one.
We may earn a commission, at no extra cost to you, when you start treatment through a link on this page. That compensation shapes one thing and we will name it: that compensation can influence placement, and the promotional CTA sits with it. It does not touch the letter. Every provider on this page is graded, on the same rubric, from its own published terms — the calculation cannot see whether a provider pays us, which is why paid rows appear in every band on the board, including the bottom one. Full details in our disclosure.
Our #1 pick
$93–$99/mo (12-mo plan)
1
CoreAge Rx
Doctor-reviewed longevity peptides and NAD+ with one published per-protocol price and built-in human support.
Best-plan rate — NAD+ "starting at" $93/mo and sermorelin $99/mo are the 12-month plan price; no one-month rate is published, and the $50–$100 consultation fee is non-refundable
U.S.-licensed clinicians review an online intake; protocols (NAD+, sermorelin, a GLP-1 microdose, and a probiotic) are filled by a 503A compounding pharmacy. Every plan includes 1:1 consults with nurses and registered dietitians and one published per-protocol figure with no separate membership and no lab gate. The advertised $93–$99 is the longest plan's rate: the refund policy states the per-month cost falls with plan length and calls the 12-month plan its best per-month price, and no one-month figure is published. Medication is refundable before pharmacy fulfilment, but the $50–$100 provider consultation fee is not — including if your prescription is declined.
Strengths
One published figure per protocol with no membership and no lab surcharge — NAD+ from $93/mo, sermorelin from $99/mo on the 12-month plan
Doctor-reviewed protocols filled by a 503A compounding pharmacy
Included 1:1 support from nurses and registered dietitians
Refund if you are not approved — minus the $50–$100 consultation fee, which the refund policy makes non-refundable
Focused longevity menu (NAD+, sermorelin, GLP-1 microdose, probiotic) without lab-heavy onboarding
Trade-offs
The advertised $93–$99 is the 12-month plan rate — the site shows no term beside it and publishes no one-month price, so the cost of trying it for a single month cannot be worked out before signing up
The $50–$100 provider consultation fee is non-refundable even if your prescription is declined, which sits awkwardly beside the refund promise on the product pages
Not a full hormone-optimization or comprehensive-lab clinic — by design
The 503A claim appears in the help centre rather than on the main site, and no dispensing facility is named — thinner pharmacy disclosure than Telos Rx, which prints both of its pharmacies' addresses
Like most longevity therapies, the protocols are compounded and not FDA-approved for anti-aging; the lifespan evidence is unproven (see our evidence review)
Start with CoreAge RxRefund if you are not approved, less the $50–$100 consult fee · $93–$99/mo is the 12-month plan rate
The rest of the field
Real longevity and hormone-optimization telehealth providers, each checked live against their own site in 2026. We only state a price where the provider published a figure we could confirm; where pricing is membership-based or revealed only in the intake, we say so plainly.
2
HealthRX
Publishes the whole NAD+ ladder, and the monthly figure is a real month-to-month rate with the visit inside it.
A LegitScript-certified, physician-supervised telehealth practice whose longevity line runs NAD+ as an injection or a nasal spray alongside sermorelin. The full price ladder is published rather than quiz-gated, and the monthly figure is a genuine month-to-month rate: the provider visit, unlimited follow-ups, supplies and shipping sit inside it, with no membership and no prepay term needed to reach the advertised price.
Strengths
A genuine month-to-month price — $161/mo injection, $134/mo nasal — with no prepay term required to reach it
Provider visit, unlimited follow-ups, supplies and shipping are included rather than billed on top
The whole price ladder is public, so the cost of moving up a dose is knowable before you start
Two NAD+ routes (injection and nasal spray) plus sermorelin under a single intake
Trade-offs
The compounding standard is stated but the pharmacy is not named — you know it is a 503A facility, not which one
The dearest rung is the one advertised — "SUBSCRIBE FROM $161/mo" is the month-to-month rate, and longer cadences go down to $129, so the headline errs in the buyer's favour rather than against it
Compounded NAD+ and sermorelin are not FDA-approved for anti-aging and the lifespan evidence is unproven
Visit HealthRX ↗Graded on the merits · verified live on the provider's own site
3
Direct Meds
A clean all-in month-to-month price on both lines — and an NAD+ and sermorelin menu the front page never mentions.
Flat month-to-month — NAD+ injection $199/mo (500mg) or $249/mo (1000mg), compounded semaglutide $297/mo, tirzepatide $497/mo, each covering medication, clinician review, supplies and 1–2 day shipping; the advertised $147 GLP-1 and $99 NAD+ figures are first-order promos
A compounded telehealth operator best known for injectable and sublingual semaglutide and tirzepatide, which also runs an Anti-Aging category of its own: injectable NAD+ at two strengths, injectable sermorelin, and a peptide skin cream. One monthly figure covers the medication, the clinician review the site prices separately at $99, all supplies and next-day courier shipping, billed month-to-month and cancellable by email with no stated penalty. Nursing staff provide ongoing care as a published stage of the program.
Strengths
One all-in month-to-month figure with the clinician visits, supplies and 1-day shipping inside it and no membership
A genuine longevity line — injectable NAD+ at 500mg and 1000mg plus injectable sermorelin — priced month-to-month like the GLP-1 plans
Cancel by email at any time — no prepay term is required to reach the published price
Nursing staff are published as providing ongoing care and support rather than a shipped vial alone
Trade-offs
The longevity line is real but buried: NAD+ and sermorelin sit in an Anti-Aging category with no prices on it, and the $199/$249 NAD+ figures appear only on a separate funnel page
The advertised "starting at $147" GLP-1 price and the $99 NAD+ price are first-order promos; the ongoing month-to-month figures are $297 and $199
The 503A standard is stated on the offer page but no facility is named, and the Anti-Aging catalogue page repeats no compounding standard at all
The main site gates pricing behind an assessment while claiming costs are "shown upfront", and the brand operates across multiple domains, so confirm you are on the official site
Its own pages contradict each other on the pharmacy: the GLP-1 offer page says 503A, while the NAD+ page (/dm-q2spc-nad/) says "dispensed by U.S.-based 503B compounding pharmacies" — and describes 503B as state-board licensed, which is the 503A arrangement
Visit Direct Meds ↗Graded on the merits · verified live on the provider's own site
4
RxSpan MD
Physician-founded practice publishing one all-inclusive month-to-month price across three NAD+ routes.
A telehealth practice founded by a named board-certified physician and available in all 50 states, whose longevity line covers NAD+ by injection, nasal spray and tablet plus sermorelin and glutathione. Pricing is published as one all-inclusive month-to-month figure — the consult, the medication, supplies and expedited shipping are inside it — with unlimited messaging and coaching instead of a separate membership.
Strengths
One all-inclusive published price per route, month-to-month, with no membership or prepay term
Three NAD+ routes (injection, nasal spray, tablet) plus sermorelin and glutathione on one intake
A named board-certified physician founder and stated availability in all 50 states
Unlimited messaging and coaching sit inside the price rather than being billed on top
Trade-offs
At $249/mo the injection is the top of this board's month-to-month range — transparent, but not cheap
The dispensing pharmacy is not named and no compounding standard is stated anywhere on the site
A prescription is not guaranteed — eligibility is reviewed after checkout
Visit RxSpan MD ↗Graded on the merits · verified live on the provider's own site
Full write-ups for the remaining 18 graded providers▾
5
Enhance MD
Real month-to-month NAD+ pricing sitting behind an advertised rate only a twelve-month prepay reaches.
Month-to-month — NAD+ injection $199/mo, sublingual wafers $99/mo (the advertised $169/mo requires a 12-month prepay)
A compounded telehealth practice offering NAD+ as an injection or as sublingual wafers. The consult is included and you are refunded in full if you are found ineligible. The month-to-month rate is $199 for the injection and $99 for the wafers; the $169/mo the site advertises is the effective rate of a twelve-month prepay, not a figure anyone is charged monthly.
Strengths
The cheapest published month-to-month NAD+ route on this board — $99/mo for sublingual wafers
Consult included, with a full refund if you are found ineligible
A genuine month-to-month option exists; no commitment is required to start
Trade-offs
The advertised '$169/mo' is a twelve-month prepay — the true month-to-month injection price is $199, and the headline does not say so on its face
A six-month lab-testing cadence applies once you are on treatment
The 503A standard is stated on the product page but no pharmacy is named, and the homepage carries no compounding claim at all
Visit Enhance MD ↗Graded on the merits · verified live on the provider's own site
6
Strut Health
The cheapest published month-to-month sermorelin on the board, with the visit and follow-up care genuinely inside it.
Month-to-month auto-refill — oral sermorelin lozenges $99/mo, injectable sermorelin from $119/mo (18% below the one-off price, which is not published); free online MD visit, follow-up care and shipping included
An asynchronous compounded telehealth whose longevity-adjacent line is sermorelin in both oral-lozenge and injectable form, alongside sublingual GLP-1 routes. A U.S.-licensed physician reviews the intake, usually within a business day, and the online MD visit, follow-up care and shipping are stated as free on the product page rather than billed on top. The published figure is an auto-refill rate you can pause, delay or cancel yourself with 48 hours' notice — a genuine month-to-month subscription, not a prepay term.
Strengths
$99/mo for oral sermorelin is the cheapest published month-to-month longevity protocol on this board
The online MD visit, follow-up care and shipping are stated as included on the product page itself
No membership, no baseline assessment and no lab gate stands between you and the published price
Self-serve pause, delay or cancel with 48 hours' notice — no prepay term at any point
Trade-offs
The headline requires auto-refill; the one-off price is 18% higher and is not published anywhere on the site
No dispensing pharmacy or facility is identified — an ACHC badge in the footer is the only signal
Review is asynchronous, so in many states you never speak to the prescriber
Does not ship to Arkansas, and the longevity line is thin — injectable sermorelin and injectable NAD+, with no oral NAD+ route and no dose ladder published
Visit Strut Health ↗Graded on the merits · verified live on the provider's own site
7
yourEra
Publishes a month-to-month NAD+ program with no contract and states what the figure buys.
Month-to-month, no long-term contracts — NAD+ from $249/mo, microdosing protocols from $179/mo, compounded semaglutide from $99/mo, tirzepatide from $169/mo; provider evaluation, medication, supplies and ongoing check-ins included
A physician-directed compounded telehealth with a real longevity line — an NAD+ program and low-dose microdosing protocols — alongside GLP-1s. Each program is published as a monthly figure covering the provider evaluation, the personalised protocol, the medication and supplies and ongoing check-ins, with no long-term contract and self-serve pause or cancel from the patient portal.
Strengths
Month-to-month with no long-term contract, and pause or cancel is self-serve from the portal
The published figure states what it covers — provider evaluation, protocol, medication, supplies and ongoing check-ins
A genuine longevity line (NAD+ plus microdosing protocols), not GLP-1 alone
Pricing is listed openly on the site rather than quiz-gated
Trade-offs
Every figure is a "from" floor — no dose tiers are published, so the cost of moving up cannot be known before you start
No dispensing pharmacy is named; the site says only "U.S. Licensed Pharmacies"
At $249/mo the NAD+ program is the top of this board's month-to-month range
Compounded NAD+ and microdosed GLP-1s are not FDA-approved for anti-aging and the lifespan evidence is unproven
Visit yourEra ↗Graded on the merits · verified live on the provider's own site
8
Sprout Health
One all-in $249 NAD+ program with the kit and overnight delivery included — behind a $199 first-month headline.
$249/mo month-to-month; clinician evaluation, injection kit and overnight delivery included (the advertised $199 is first month only)
A LegitScript-certified telehealth practice selling NAD+ as a single injectable program: the clinician evaluation, the injection kit and overnight delivery are covered by one monthly figure with no membership. The ongoing price is $249/mo — the $199 the site leads with is an introductory first-month rate that steps up at the first refill.
Strengths
One all-in monthly figure covering the clinician evaluation, the injection kit and overnight delivery
Month-to-month — no prepay term or membership stands between you and the published price
Low-friction start; the program is not gated behind a lab panel
Trade-offs
The advertised '$199' is a first-month rate only — from the first refill the price is $249/mo
At $249/mo for a single injectable route it is the top of this board's month-to-month range
The dispensing pharmacy is not named, and Sprout's own press release declines to say whether it compounds under 503A or 503B — it tells you to ask the pharmacy yourself
Visit Sprout Health ↗Graded on the merits · verified live on the provider's own site
9
System Labs
A real NAD+ and sermorelin menu with prices on the page — but every figure printed is a first month, not a rate you hold.
First-month teaser pricing against a struck-through standing rate — NAD+ "$149" struck through to "$89 /first mo", sermorelin "Monthly Supply (5mg)" "$219" struck through to "$109 /first mo", compounded GLP-1/GIP "$179" struck through to "$99 /first mo"
A compounded telehealth practice (operator: System Laboratories, Inc.) whose whole menu is the longevity stack rather than a weight-loss shop with a peptide bolt-on: NAD+ as an injection and as a nasal spray, sermorelin as an injection and as an oral compound, glutathione injection, MIC+B12, GHK-CU cream, and compounded GLP-1/GIP. Its product landers publish a price openly, which most of this board does not — but every figure on them is a first-month rate shown against a struck-through standing rate, so the number in large type is not the number you pay from month two. Each lander includes injection supplies, 2-day temperature-controlled shipping, ongoing support from a real care team, and 20% off a Rythm blood test.
Strengths
The menu is the longevity stack itself — NAD+ by injection and nasal spray, sermorelin by injection and orally, plus glutathione — not a GLP-1 shop with one peptide attached
A price is published on the product lander rather than held behind the intake, and the standing rate is shown beside the promotional one
"Injection supplies included", 2-day temperature-controlled shipping and "Ongoing support from a real care team" are stated inside the price on every lander
LegitScript Certified badge published on its own site
Trade-offs
Every published figure is a first-month teaser against a struck-through standing rate — "$89 /first mo" from "$149", "$109 /first mo" from "$219" — so the large number is not what a second month costs
The site's own /nad path is an intake questionnaire rather than a product page; the prices above exist only on the product landers, which is not where a reader browsing the site arrives
Nothing on the lander states whether the clinician visit is included in the published price, so the all-in first payment cannot be worked out before signing up
No dispensing or compounding pharmacy is identified, and no compounding standard is stated — the LegitScript badge is an accreditation, not a pharmacy
Visit System Labs ↗Graded on the merits · verified live on the provider's own site
10
Telos Rx
The only board member that names its dispensing pharmacies — and the headline price is the longest plan, not a month.
Plan-length pricing — NAD+ nasal spray "as low as $116/mo" against a $249 list price, sermorelin "as low as $125/mo" against $299; the single-month rate is never published
A compounded telehealth practice whose live catalogue is narrower than its positioning suggests — seven product pages: NAD+ nasal spray, sermorelin, PT-141 and four GLP-1 products. It names both dispensing pharmacies with street addresses, which is the most pharmacy-transparent disclosure on this board, but publishes no table showing what any individual plan length costs.
Strengths
Both dispensing pharmacies are named with addresses — VialsRX (Houston, TX) and Jungle Jim's / F&F Pharmacies (Fairfield, OH) — which no other row on this board does
24/7 unlimited messaging with the medical team is inside the subscription
Lab work is included at no extra cost rather than billed as a gate
The widest longevity peptide menu here, under a single intake, with cancel-anytime and no stated penalty
Trade-offs
No single-month price is published anywhere — "as low as $116/mo" is explicitly the longest plan, and the only month-shaped figures on the page are the $249 and $299 struck-through list prices
Neither named pharmacy is described as a 503A facility, so the compounding standard is still unstated
Jungle Jim's is unlicensed in ten states (CA, NV, NJ, NC, TX, MA, MS, NH, WV, DE) and cannot dispense sterile compounds
Most of the menu is research-grade peptides with limited human data and none of it is FDA-approved for anti-aging
Visit Telos Rx ↗Graded on the merits · verified live on the provider's own site
11
Shed
Publishes a headline NAD+ price but not what it buys — the number you commit to arrives inside the portal.
Headline $169/mo injection, $144/mo nasal spray, $169/mo oral — the final price is quoted only inside the portal
A metabolic telehealth practice with an NAD+ line in three routes — injection, nasal spray and oral. Headline monthly figures are published, but the price you are actually charged is quoted only after you enter the portal, and the site does not state whether a provider consult is included in it. On a rubric built around a single all-in figure you can see before committing, that is the failure, not a footnote.
Strengths
Three NAD+ routes — injection, nasal spray and oral — available from one intake
Headline monthly figures are at least published, and the nasal route at $144/mo is among the cheaper here
Trade-offs
Its own Terms §11.1 require a minimum two-month commitment — early cancellation "does not release you from payment obligations and will not result in a refund or credit", so the monthly headline is not a monthly plan
Billing may run every 28 days rather than monthly, which is 13 charges a year, not 12
§14.1/14.2 of the live Terms print the Care Membership price as an unfilled template placeholder — "$[X]" and "$[Y]" — so the published contract has no price in it
§10 and §40 state that no part of the membership fee is payment for medical services, so the consult is published as NOT included
The final price is quoted only inside the portal — the published headline is not the figure you commit to
It does not publish whether a provider consult is included, so the all-in cost cannot be known before signing up
No LegitScript badge or founding year is published on the marketing pages; the parent (Shed Holdings, LLC) and three dispensing pharmacies are named only inside the Terms, not where a buyer would look
Its 503A claim is hedged — Shed says it partners with "both 503A and 503B pharmacies" and names neither, so which standard applies to your vial is not knowable in advance
Visit Shed ↗Graded on the merits · verified live on the provider's own site
12
MadeMed
NAD+ by two routes, but no month-to-month plan exists — the shortest way in is a three-month prepay.
No month-to-month plan — $209/mo on a 3-month plan ($627) or $199/mo on 6 months ($1,194); a CMP blood test is required first
A LegitScript-verified compounded telehealth offering NAD+ as an injection and as a nasal spray alongside sermorelin, with prices published dose by dose. What is not on offer is a monthly plan: the shortest term is three months billed at $627 up front ($209/mo), with six months at $1,194 ($199/mo). A comprehensive metabolic panel is required before treatment and the site does not state that its cost is covered.
Strengths
NAD+ by two routes — injection and nasal spray — plus sermorelin under one intake
Prices are published dose by dose, so the cost of a titrated protocol is knowable up front
Board-certified physician review, with the visit included and free overnight shipping
Trade-offs
There is no one-month plan at all — the shortest commitment is three months paid up front, so '$209/mo' is a prepay rate rather than a monthly price
A comprehensive metabolic panel is required before treatment and its cost is not stated as included, so the true first payment cannot be worked out from the site
Available in 40 states rather than nationwide, and the dispensing pharmacy is not named
Visit MadeMed ↗Graded on the merits · verified live on the provider's own site
13
Try Ageless
Every advertised longevity price is an intro-code rate, and the site says outright the real figure arrives after review.
1-month supplies at list — NAD+ injection $249, NAD+ tablets $199, sermorelin injection $176, sermorelin nasal spray $199; the advertised $199 / $149 / $126 figures are limited-time intro-code prices, and the final amount is set after clinical review
An online storefront whose longevity menu spans NAD+ by injection and flex-dose tablet, sermorelin by injection and nasal spray, low-dose naltrexone, methylene blue and MIC+B12, next to a TRT line and compounded GLP-1s. Products are sold as one-month supplies rather than a membership, and a licensed clinician reviews the questionnaire before anything ships. The problem is the number: each product page shows a struck-through list price beside an "INTRO SAVINGS" figure reachable only with a limited-time code, then states that "exact pricing depends on your prescribed dose" and "final amount is shown after clinical review".
Strengths
A genuinely broad longevity stack — NAD+, sermorelin, LDN, methylene blue — in both injectable and oral formats under one intake
Sold as one-month supplies, so no membership or prepay term is required to start
Clinician review is included, with free shipping and a 30-day satisfaction guarantee on unopened medication
Trade-offs
Every advertised longevity price is a limited-time intro-code rate: the real list prices are $249 (NAD+ injection) and $176 (sermorelin injection), not the $199 and $126 shown
The page states the final amount is set after clinical review, so no published figure is the one you pay
No named pharmacy, no named medical group and no published state-availability list
The oral GLP-1 drops and troches lack robust absorption evidence against injectables
Visit Try Ageless ↗Graded on the merits · verified live on the provider's own site
14
Gala Health
"$179/mo, no hidden fees" is a twelve-month subscription rate; no month-to-month price is published at all.
No month-to-month price published — the advertised $179/mo is calculated on a yearly subscription plan, and the cheapest plan the site actually quotes is $199/mo on a 3-month term; the microdosing "longevity protocol" is $149/mo on the same yearly basis; brand Ozempic $1,299/mo
A GLP-1 telehealth operator licensed in all 50 states, selling compounded tirzepatide, a low-dose "longevity protocol" microdosing tier, brand Ozempic and an adjacent HRT/menopause line. Medical care is delivered by affiliated practices including OpenLoop-affiliated groups. The homepage leads with "$179/mo all doses, no hidden fees" — and its own asterisk says that figure is "calculated based on a yearly subscription plan", while the FAQ quotes $199/mo on a three-month plan as the entry point.
Strengths
Licensed providers in all 50 states with a free online assessment and no insurance required
Dose increases are explicitly at no additional cost, so titration does not reprice the plan
A low-dose microdosing tier is offered and framed as a longevity protocol rather than weight loss alone
Trade-offs
The headline $179/mo is a twelve-month subscription rate, not a monthly price — the site's own footnote says so and the FAQ's cheapest quote is $199/mo on a three-month plan
No month-to-month figure is published anywhere, so the cost of a single month cannot be worked out from the site
"No hidden fees" sits directly above the footnote that redefines the price — the two claims are on the same screen
No pharmacy is named beyond "a wide network across all 50 states", and no support is published as included
The only row here with no NAD+, no peptide and no diagnostic line at all — the "longevity protocol" is a microdosed GLP-1, and the hormone menu is menopause symptom care rather than longevity medicine
Visit Gala Health ↗Graded on the merits · verified live on the provider's own site
15
Wellorithm
The sermorelin and NAD+ pages exist and carry a price — they are also unlinked, unlisted, and printed with somebody else's copy on them.
Sermorelin "$150 first month" then "$200/mo*" — the asterisk is not resolved on that page, and where Wellorithm does publish it (the NAD+ page) it reads "Price shown applies to 500mg (2.5mL) 3-month plan paid upfront or with buy now, pay later programs. Actual price will depend on product and plan prescribed"; the four compounded GLP-1 SKUs carry no public price at all
A facilitator-model telehealth: its own Terms state that "Wellorithm acts as a facilitator, connecting users with licensed healthcare professionals through its Professional Entities. The company itself does not diagnose, treat, or practice medicine", with asynchronous provider review after an online evaluation. Its longevity line is a sermorelin injection ("5mL (10mg) vial and homekit included", free expedited shipping, FSA & HSA eligible) and an NAD+ injection; there is no oral, sublingual or nasal sermorelin route. Alongside it sits compounded semaglutide and tirzepatide in injection and oral dissolving tablets, whose pricing is gated behind the site's quiz, plus four branded pens sold at Ozempic $1,119/mo, Wegovy $899/mo, Mounjaro $1,399/mo and Zepbound $1,119/mo.
Strengths
A sermorelin injection and an NAD+ injection are both listed "In Stock" with a figure printed on the page — the compounded GLP-1 line beside them has no public price at all
"5mL (10mg) vial and homekit included", free expedited shipping and FSA & HSA eligibility are stated on the sermorelin page rather than added later
Trade-offs
The "$200/mo*" carries an asterisk that page does not resolve; the footnote Wellorithm publishes with that same figure elsewhere conditions it on a "3-month plan paid upfront" and adds that "Actual price will depend on product and plan prescribed"
The sermorelin page carries leftover NAD+ copy — "NAD+ boosts mitochondrial function to power your day." and "Support DNA repair and longevity enzymes like SIRT1." — on a page selling a growth-hormone secretagogue
All four branded-drug pages repeat the NAD+ 500mg pricing footnote, which describes nothing on them, and the Ozempic and Zepbound pages each print $1,119 in the hero and $1,199 in the call to action
Its Terms bill "every 28 days, and payments are non-refundable once processed" — thirteen charges a year, not twelve, and no refund once one clears
The homepage says "Serving All 50 States" while other pages say 49, excluding Louisiana — the site contradicts itself on where it can treat you
The sermorelin and NAD+ pages are not linked from the site's own navigation and are absent from its sitemap, so the only longevity line here is one a reader cannot find by browsing
The compounding pharmacy is never named — "Compounded in the U.S.A" is the whole disclosure — and the company's own Terms say it does not practice medicine
Visit Wellorithm ↗Graded on the merits · verified live on the provider's own site
16
Lifeforce
Premium, lab-heavy health-optimization membership with quarterly retesting.
$349 baseline assessment, then $129/mo membership; therapies extra
A phlebotomist-drawn at-home panel of 40–50+ biomarkers is interpreted by physicians, who build a program of nutraceuticals plus hormone and peptide therapies. Membership includes quarterly retesting and a health coach; recommended interventions are billed on top.
Strengths
Deep biomarker panel (40–50+ markers) with quarterly retesting
Personal health coach and physician-built protocol
Publishes its dispensing pharmacies by name and address — Tailor Made Compounding, GoGoMeds and Precision Pharmacy — which only Telos Rx also does
Strong fit for users who want full data-driven optimization
Trade-offs
High entry cost: $349 baseline plus $129/mo before any therapy
Lab-heavy and membership-gated — the opposite of a flat per-protocol price
Recommended hormones/peptides/nutraceuticals are additional spend
Visit Lifeforce ↗Graded on the merits · verified live on the provider's own site
17
AgelessRx
Broad longevity catalog (NAD+, metformin, sermorelin, GLP-1) with no required membership.
Pricing varies / per-treatment (no flat price published on site)
Online assessment reviewed by U.S.-licensed providers; prescriptions are filled through partnering pharmacies and shipped within 5–7 business days. The menu spans NAD+, metformin, low-dose naltrexone, glutathione, GLP-1 support, sermorelin, and a biological-age test. No membership is required to order.
Strengths
Wide longevity menu in one place (NAD+, metformin, LDN, sermorelin, GLP-1)
No mandatory membership — you can order individual treatments
Optional biological-age testing for those who want it
Trade-offs
No transparent flat price on the public site — totals are revealed in the intake and vary by treatment
The FAQ states every partner pharmacy is 503A certified, but no individual facility is named
Nurse / dietitian support is not part of the headline offer
Visit AgelessRx ↗Graded on the merits · verified live on the provider's own site
18
Function Health
Test-first DTC membership — 100+ biomarkers and a biological-age read for a flat annual fee.
$365/year (one flat annual membership)
A flat annual membership covers 100+ biomarkers across two blood draws a year, a biological-age estimate, and physician review that flags abnormal results. It is a diagnostics-first program: it tells you what to look at, but treatment is largely handed off elsewhere rather than prescribed and managed in-house.
Strengths
Genuinely flat, transparent annual price ($365/yr) with no per-test surprises
Very broad panel — 100+ biomarkers across two draws plus a biological-age read
Physician outreach on out-of-range results
Trade-offs
Diagnostics-first — it largely tells you what is wrong rather than treating it, so you still need a prescriber for NAD+/peptides/GLP-1
Biological-age outputs vary by the method used and should be read cautiously
No included nurse or dietitian protocol support the way a treatment program offers
At-home lab testing of 40+ biomarkers starts the program, followed by a telehealth physician consult and a personalized plan. Longevity is one track within a broader testosterone- and hormone-optimization platform; medication costs are separate from the membership fee.
Strengths
Comprehensive at-home biomarker panel for data-driven users
Both men's (TRT) and women's (HRT) hormone tracks
Low-cost basic membership tier for those who just want monitoring
Trade-offs
Lab-gated and membership-based — medication is billed on top of the monthly fee
Hormone/TRT framing; longevity peptides are not the core focus
More onboarding than a single flat-priced protocol
Visit Hone Health ↗Graded on the merits · verified live on the provider's own site
20
Next Health
In-clinic longevity membership — NAD+ IV drips, peptide therapy and functional labs across multiple cities.
Membership-based (tiered monthly plans); NAD+ IV billed per session
A network of in-person clinics built around NAD+ IV therapy, peptide therapy, IV/longevity drips, and functional-lab panels, sold through tiered monthly memberships with provider consults. The membership gates access, and individual services such as NAD+ infusions are billed per session on top of the recurring fee.
Strengths
In-person clinics with provider consults and supervised IV administration
Broad menu — NAD+ IV, peptides, longevity drips, functional labs in one place
Tiered membership lets lighter users start lower
Trade-offs
Membership-gated with per-session billing on top — the opposite of a single flat protocol price
Wellness-lounge positioning; the evidence for NAD+ IV in healthy adults is weak
Requires visiting a physical clinic rather than a flat-priced telehealth protocol
Visit Next Health ↗Graded on the merits · verified live on the provider's own site
21
Marek Health
Deep-diagnostic hormone-optimization and peptide telehealth, billed pay-per-use rather than flat.
A guided-optimization model centered on some of the deepest diagnostic panels in the category, paired with TRT, hormone optimization, peptide therapy, and GLP-1 support. You pay an intake deposit and then per-service: the lab panels, the therapy, and follow-ups are each billed separately rather than under one flat monthly figure.
Strengths
Among the deepest diagnostic panels in the category for data-driven users
Guided hormone-optimization with peptide and GLP-1 options
Pay-per-use means no mandatory recurring membership to start
Trade-offs
No single flat price — intake deposit plus separate per-service billing makes the true cost hard to see upfront
Hormone/TRT-optimization framing rather than a focused longevity-peptide protocol
Peptide marketing leans on claims that are not backed by human lifespan evidence
Visit Marek Health ↗Graded on the merits · verified live on the provider's own site
22
Fountain Life
The premium concierge ceiling — full-body and brain MRI, coronary CTA and AI screening at concierge prices.
Concierge tiers from roughly $2,995/year up to ~$19,500/year
A high-touch, in-person concierge program built around imaging-grade diagnostics — full-body and brain MRI, coronary CTA, AI-assisted cancer screening, and quarterly blood panels with a concierge physician. It is the premium ceiling of the category: aspirational early-detection diagnostics rather than a price-competitive treatment protocol.
Strengths
Imaging-grade diagnostics (full-body/brain MRI, coronary CTA, AI screening) few competitors match
Concierge physician oversight and quarterly biomarker panels
Strong fit for users who want the most comprehensive early-detection workup available
Trade-offs
Concierge pricing (up to roughly $19,500/yr) puts it far above a flat per-protocol telehealth plan
Early-detection framing can over-screen otherwise-healthy people and surface incidental findings
In-person and diagnostics-led — not a flat-priced NAD+/peptide/GLP-1 protocol
Visit Fountain Life ↗Graded on the merits · verified live on the provider's own site
Want the marks side by side again? Back to the report card — every graded provider, its grade, price and six marks on one screen. “Optional” labs means the provider may offer or suggest testing but does not gate the basic plan on it; “Yes” means the program starts with required lab work. Confirm current terms with the provider before starting.
Why CoreAge Rx grades first
CoreAge wins on the fundamentals rather than on any claim that a peptide is a fountain of youth. It publishes one figure per protocol — NAD+ from $93/month, sermorelin from $99/month — with no membership and no lab surcharge to discover later. The intake is reviewed by U.S.-licensed clinicians, protocols are filled by a 503A compounding pharmacy, and every plan includes 1:1 consults with nurses and registered dietitians. Two things to know before you buy, and we hold every other row to the same test: those figures are the 12-month plan rate — no one-month price is published — and the $50–$100 consultation fee is non-refundable even if your prescription is declined.
We are equally honest about the science: outside of GLP-1 cardiovascular outcomes, the human lifespan evidence for these therapies is unproven, and compounded longevity protocols are not FDA-approved for anti-aging. This ranking is about provider quality, value, and experience — not a promise of a longer life. Read the full picture in our longevity-medicine evidence review before deciding.
We do not run sponsored reviews or accept payment to change a grade. Each provider scores out of 14 on the five factors below. Price transparency carries the most weight because hidden recurring fees, prepay terms and intro-month headlines are the most common way longevity programs end up costing far more than they first appear — and the longevity line carries the same weight, because a spotless price on a product this page does not rank is not a longevity recommendation. Required lab work is printed on every row but scores neither way: it is a trade-off, not a failing.
Price transparency
4 points
A single, all-in price you can see before you commit, that a month-to-month buyer actually pays. A headline reachable only on a 6- or 12-month prepay, an intro-code rate, or a figure superseded by 'final price after review' scores nothing. Worth double, because a price you cannot see is the most expensive thing on this board.
Longevity line
4 points
Does the provider actually sell what this page ranks — NAD+, peptides or sermorelin, hormone optimization, or longevity diagnostics? Full marks for a published line of the business, half for something adjacent, nothing for a weight-loss shop on a longevity board. Worth double, and the A band sits above what a provider with no longevity line can reach at all.
Clinical oversight
2 points
The provider visit is included in the published price rather than billed on top or left unstated — real review by a U.S.-licensed clinician, with a path to decline candidates who are not appropriate.
Pharmacy quality
2 points
Both points go to a provider that publishes a 503A claim on a surface it controls — its own site, help centre or official press material — whether or not it names the facility. One point goes to a pharmacy named outright, address and all, without a stated classification. 'Partner pharmacies', 'a licensed U.S. pharmacy' and an unnamed network score zero, and so does a 503A claim made only by somebody else's review site.
Human support
2 points
Included access to nurses, dietitians, coaching or unlimited clinical messaging — not just a shipped vial — and included in the price rather than sold as an upgrade.
Fourteen points to a grade. 11–14 earns an A, 8–10 a B, 0–7 a C. Two rules set those lines, both fixed before any provider was scored: a C is half the scale or less, and the A floor sits one point above the 10 that a provider with no longevity line can reach with everything else perfect — so the top band on a longevity board is closed to a business that does not sell longevity medicine. No provider can be moved across a boundary after the fact. The calculation takes the provider's own published terms and nothing else; it is not given, and cannot read, whether we hold a commercial relationship with the provider. Partners are still listed first on this page — that is a placement we disclose, and it is the only thing our funding moves.
Read the evidence first
A provider ranking is only half the decision. Understand what longevity medicine can and cannot do before you start:
This page is informational and not medical advice. Longevity and anti-aging therapies are available by prescription after clinician review; most are compounded and not FDA-approved for anti-aging, and their effect on human lifespan is unproven. Talk to a licensed provider about whether any protocol is appropriate for you.